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PROGRAMME
Scientific Programme
PROGRAMME OVERVIEW:
Tuesday May 2 | Albufeira Municipality
11:00 - 16:00
FRM23 meets Albufeira students | Albufeira Municipality
18:00
Neuroscience exhibition opening - 'Unraveling the brain: a view of the Neurosciences' | Albufeira Municipality
21:00
Welcome reception | Albufeira Municipality
Wednesday 3 May | Salgados Palace & Congress Center
09:00 - 09:30
FRM23 Opening Session - Auditorium
- Clévio Nóbrega, FRM 2023 Chair
- Ana Cristina Rego, SPN President
- Irene Tracey, FENS President
- José Carlos Rolo, Mayor of Albufeira Municipality
09:30 - 11:00
Symposium 1 - 'New vistas on stress, brain and behavior' - Room Monchique
Chairs
Symposium 2 - "Next-generation molecular tools for dissecting brain circuits at single cell level (sponsored by the Sociedade Portuguesa de Bioquímica)" - Auditorium
- Mathias V. Schmidt (Max Planck Institute of Psychiatry, Munich, Germany)
- Carmen Sandi (Brain Mind Institute, Ecole Polytechnique Federale de Lausanne, Switzerland)
- Carmen Sandi (EPFL, Switzerland) - "Brain mitochondria and metabolism at the core of anxiety and related behaviors"
- Mathias V. Schmidt (Max Planck Institute of Psychiatry, Munich, Germany) - "Brain mechanisms bridging the link from stress to psychiatric and metabolic disorders"
- Caroline Menard (Université Laval, Quebec, Canada) - "Blood-brain barrier adaptations underlie stress responses and mood disorders"
- Patrícia Gomes (Life and Health Sciences Research Institute, ICVS, University of Minho, Portugal) - "Isolation of spontaneously-released brain extracellular vesicles: implications for brain pathology"
- Heather K Macpherson (Queensland Brain Institute, Australia) - "Inflammation and dopamine dysregulation underlying anhedonic phenotype induced by adrenocorticotrophin hormone in antidepressant-resistant rats"
Chairs
Symposium 3 - 'Dysregulation of extracellular matrix in neurodegenerative diseases' - Room Tavira
- Patrícia Monteiro (Faculty of Medicine, University of Porto, Portugal)
- Zhanyan Fu (Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA) - "A comprehensive single-cell atlas of thalamic reticular nucleus, a key node of the brain’s attentional network"
- Klaus Eyer (ETH Zürich, Switzerland) - "Single-cell deep phenotyping of cellular functionalities"
- Matthew Holt (i3S-Institute for Research & Innovation in Health, Porto, Portugal) - "Blood-brain barrier crossing viral vector systems: unique opportunities for minimally invasive, brain wide gene delivery"
- Muhammad Tibi (Israel Institute of Technology, Israel) - "A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types"
- Luís Jacinto (Faculty of Medicine, University of Porto, Portugal) - "Graphene bioelectronics for ultra-sensitive neurochemical sensing"
Chairs
Symposium 4 - 'Diseases caused by autoantibodies against neuronal cell-adhesion proteins: cellular and molecular mechanisms' - Room Alcoutim
- Eva Sykova (Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia)
- Eva Sykova (Slovak Academy of Sciences, Slovakia) - "Dysregulation of ECM in health and disease affect brain diffusion parameters and extrasynaptic transmission"
- Constanze Seidenbecher (Leibniz Institute for Neurobiology, Germany) - "Dysregulation of Hyaluronan-based ECM in epilepsy, Alzheimer’s disease, and ALS"
- Juan Nacher (Universitat de Valencia, Spain) - "Dysregulation of ECM in psychiatric disorders: Impact on the connectivity of inhibitory networks"
- Federico N. Soria (Achucarro Basque Center for Neuroscience, Leioa, Spain) - "A matrix microglia feedback loop underlies alterations in the brain extracellular space in parkinsonian mice"
Chairs
- Luís Ribeiro (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal)
- Ester Coutinho (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal)
- Angela Vincent (Nuffiled Deprtment of Clinical Neurosciences, University of Oxford, England) - "CASPR2 and LGI1 antibodies associated neurological disorders: antibodies and mechanisms"
- John Dawes (Nuffiled Deprtment of Clinical Neurosciences, University of Oxford, England) - "Chronic neuropathic pain and CASPR2-antibodies: uncovering novel molecular pathways"
- Lidia Sabater (Clinic Hospital, University of Barcelona, Spain) - "Patients’ IgLON5 autoantibodies interfere with IgLON5-protein interactions"
- Débora Serrenho (Center for Neurosciences and Cell Biology, University of Coimbra, Portugal) - "Human anti-CASPR2 autoantibodies impact synaptic transmission and neuronal excitability"
11:00 - 11:15
Break
11:15 - 12:15
Plenary Lecture 1 - "Exuberance and plasticity in the developing cortex" - Auditorium
Chairs
- Paola Bovolenta (Center for Molecular Biology Severo Ochoa, CSIC-UAM, Madrid, Spain)
- Teresa Summavielle (i3S - Institute for Research & Innovation in Health, Porto, Portugal)
Speaker(s)
- Marta Nieto (Centro Nacional de Biotecnología, Madrid, Spain)
12:15 - 13:15
Lunch break
13:15 - 14:15
Poster Session I - Room Silves
14:15 - 14:45
SPN Best Manuscript Prize Lecture - Luísa Pinto - "Impact of adult hippocampal cytogenesis modulation on brain physiology and behavior" - Room Alcoutim
Chairs
- Ana Cristina Rego (SPN President) / Tiago Gil Oliveira (SPN Vice-President)
- Luísa Pinto (Life and Health Sciences Research Institute, ICVS, University of Minho, Portugal)
EBRAINS Research Infrastructure: a solution driven approach for studying neurodegenerative disorders - Room Tavira
Chair
- Edith EUAN-DIAZ (EBRAINS)
- Petra Ritter (Berlin Institute of Health & Dept. of Neurology, Charité University Hospital Berlin, Germany)
- Thibault GRIEZ, EBRAINS Infrastructure Coordinator
EJN Best Publication Award Lecture - "Distinct contributions of alpha and theta rhythms to perceptual nd attentional sampling" - Auditorium
Speaker(s)
- Rene Michel (University of Munster in Germany)
14:45 - 16:15
Symposium 5 - Molecular Mechanisms of Synaptopathy in Movement Disorders (sponsered by SPDMov - Sociedade Portuguesa de doenças do Movimento) - Room Monchique
Chairs
- Tiago F. Outeiro (University Medical Center Goettingen, Goettingen, Germany)
- Arianna Bellucci (Department of Molecular and Translational Medicine, University of Brescia, Italy) - “Synaptic pathology in Parkinson’s disease: focus on the alpha- synuclein/synapsin III interplay”
- Flaviano Giorgini (Department of Genetics and Genome Biology, University of Leicester, England) - “Rab GTPases and synaptic dysfunction: uncovering mechanisms and therapeutic strategies in protein misfolding disorders”
- Eulàlia Martí (Institute of Neurosciences, University of Barcelona, Spain) - “RNA pathogenesis in Huntington’s disease”
- Kaitlyn Cramb (Oxford Parkinson’s Disease Centre, University of Oxford, England) - “Defective dopamine release from iPSC-derived dopamine neurons harbouring Parkinson’s disease-associated SNCA-triplication”
Symposium 6 - 'Recent advancements in computational glioscience: from point models to geometrical-accurate simulations' - Auditorium
Chairs
- Corrado Calì (Department of Neuroscience “Rita Levi Montalcini”, Università degli Studi di Torino, Torino, Italy and Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Torino, Italy)
- Renaud Jolivet (Maastricht University, Netherlands) - “Energy and Information at the Tripartite Synapse”
- Audrey Denizot (Okinawa Institute of Science and Technology, Japan) - “Dissecting the functions of astrocyte nano-architecture using voxel-based computational models”
- Marja-Leena Linne (Tampere University, Finland) - “Modeling astrocyte-neuron interactions: From synapses and networks to cognition”
- Nicola Mendini (University of Sheffield, England) - "Topological maps enable receptive field expansion in cortical processing hierarchies"
- João Luís Fernandes Machado (Life and Health Sciences Research Institute, ICVS, University of Minho, Portugal) - "Astrocyte structural heterogeneity in the mouse hippocampus"
Symposium 7 - 'Using small brains to gain deep mechanistic insights into chemosensory processing and plasticity - Room Tavira
Chairs
- Carlos Ribeiro (Champalimaud Foundation, Lisbon, Portugal)
- Silke Sachse (Max Planck Institute for Chemical Ecology, Germany) - “Olfactory processing and plasticity in the fly brain”
- Emre Yaksi (Kavli Institute for systems neuroscience, Norway) - “The role of GnRH in olfactory computations and regulating feeding behaviors”
- Carlos Ribeiro (Champalimaud Foundation, Lisbon, Portugal) - “The gourmet fly: dissecting the mechanisms by which internal states shape brain function and behavior”
- Ulises Rey (University of Vienna, Austria) - "Global brain dynamics at a single neuron resolution in a freely moving animal"
- Yoh Isogai (Sainsbury Wellcome Centre for Neural Circuit and Behaviour, University College London, England) - "Molecular and neural detection of pheromones"
Symposium 8 - 'Sex differences in stress responses: mechanisms of resilience and vulnerability to the development of mental disorders - Room Alcoutim
Chairs
- Patrizia Campolongo (Department of Physiology and Pharmacology, Sapienza University of Rome, Italy)
- Debra Bangasser (Center for Behavioral Neuroscience, Georgia State University, USA) - “Early resource scarcity causes sex-specific changes in motivated behavior”
- Fatiha Chigr (Faculty of Sciences and Techniques, University Université Sultan Moulay Slimane, Morocco) - “Sex differences of prenatal stress on adolescent rodents”
- Patrizia Campolongo (Department of Physiology and Pharmacology, Sapienza, Italy) - “Modulation of memory for traumatic experiences: sex dependent trajectories in the development of post-traumatic stress disorders”
- Adriano Lama (University of Naples Federico II, Italy) - “Gender-related response to lipopolysaccharide injection: the bond between neonatal infections and obsessive-compulsive disorder”
16:15 - 16:30
Break
16:30 - 17:30
Poster Session II - Silves
17:30:18:30
Plenary Lecture 2 - 'A cup of coffee to preserve memory? The role of the adenosine neuromodulation system'- Auditorium
Chairs
- Ana Maria Sebastião (Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisboa, Portugal)
- Rodrigo Cunha (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal)
18:30 - 20:00
Special Events
Going the extra mile: Advice for Young Neuroscientists - Room Tavira
Chairs
- David Brito (Algarve Biomedical Center Research Institute, Univeristy of Algarve, Faro, Portugal)
- Richard Sever (Cold Spring Harbor Laboratory, USA) - "Preprints: communicating at the speed of science"
- Àlex Gómez-Marín (Instituto de Neurociencias (CSIC-UMH), Spain) - "The end of inquiry ("that is all very fine, but get your next grant and move on")?!"
- Benjamin Aaron Rein (Stanford University, USA) - "Leveraging Social Media for Public Engagement with Science"
Animal Research: Time to Talk! - Room Alcoutim
Chairs
- Kirk Leech (European Animal Research Association)
- Kirk Leech, European Animal Research Association (EARA)
- Roman Stilling, affiliated with CARE, EARA and TVV (Tierversuche verstehen, Germany)
FENS History Committee - Contributions generated from the Iberian Peninsula to the foundation of modern Neuroscience - Room Monchique
Chair
- Fernando de Castro (Instituto Cajal-CSIC, Spain)
- Joao Relvas (i3S -Institute for Research & Innovation in Health, Porto, Portugal)
- Fernando de Castro (Instituto Cajal-CSIC, Spain)
- Isabel Amaral (FCT_NOVA, Nova University of Lisbon, Portugal)
19:30 - 20:30
SPN general assembly - Auditorium
Thursday 4 May | Salgados Palace & Congress Center
08:45 - 09:45
Plenary Lecture 3 - "Pathogenic Mechanisms in the Tauopathies" - Auditorium
Chairs
- Tiago Gil Oliveira (Life and Health Sciences Research Institute (ICVS), University of Minho, Portugal)
- Isaura Tavares (Faculty of Medicine, University of Porto, Portugal)
- Karen Duff (U.K. Dementia Research Institute, University College London, UK)
09:45 - 09:55
Juan Lerma - European Brain Council: 20 years of advocacy for brain research - Auditorium
Speaker(s)
- Juan Lerma (Institute of Neurosciences UMH-CSIC, Spain)
09:55 - 10:00
Break
10:00 - 11:00
Poster Session III - Room Silves
Special event – EJN Workshop: Handling, Review and Publication of EJN Manuscripts - Room Albufeira
Chairs
Femtonics - "Variations on a theme, or the diverse purpose of acousto-optic imaging" - Room Monchique- John Foxe (Albert Einstein College of Medicine, New York, USA)
- Paola Bovolenta (CSIC-UAM, Madrid, Spain)
- Yoland Smith (Emory National Primate Research Center, USA)
11:00 - 12:30
Symposium 9 - 'Circuit dysfunction in pre-clinical models of movement disorders' - Room Monchique
Chairs
- Joaquim Alves da Silva (Champalimaud Foundation, Lisbon, Portugal)
- Amanda Pocratsky (University College London, England) - “Pathophysiology of Dyt1 dystonia is mediated by spinal cord dysfunction”
- Filipa França de Barros (Champalimaud Foundation, Portugal) - “Opposing changes in the activity of direct and indirect pathways within the striatum of freely moving dyt-tor1a dystonic mice”
- Patricia González Rodriguez (Instituto de Biomedicina de Sevilla, Spain) - “Genetic disruption of mitochondrial complex I triggers progressive, levodopa-responsive Parkinsonism with nigral determinants”.
- Thomas Pass (University of Cologne, Germany) - “Preserved Motor Function and Striatal Innervation Despite Severe Degeneration of Nigral Dopamine Neurons Upon Mitochondrial Dysfunction”
Symposium 10 - 'Nanoscale imaging to study the aging brain' - Auditorium
Chairs
- Joana Ferreira (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal)
- Juan A. Varela (University of St Andrews, St Andrews, Scotland, UK)
- Joana Ferreira (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal) - “Nanoscale organization in synapses and potential impact for cognitive resilience in aging”
- Jan Tønnesen (Achucarro Basque Center for Neuroscience, University of the Basque Country, Spain) - “STED microscopy for studying age-related changes to the structure and dynamics of the neuropil”
- Juan A. Varela (School of Physics and Astronomy, University of St Andrews, England) - “Clearance of brain extracellular solutes in healthy aging and in Alzheimer’s disease models at the nanoscale”.
- Claudia Guimas Almeida (NOVA Medical School, Universidade Nova de Lisboa, Portugal) - “Imaging the Endolysosomal System Dysfunction in the Normal Aging Brain: Relevance for Age-dependent Synapse Loss”
Symposium 11 - 'Plasticity of innate behaviors' - Room Tavira
Chairs
- Nicolas Gutierrez-Castellanos (Champalimaud Foundation, Lisbon, Portugal)
- Susana Q. Lima (Champalimaud Foundation, Lisbon, Portugal)
- Tiago Branco (Sainsbury Wellcome Centre, England) - ”Modulation of escape behavior”
- Silvana Valtcheva (University of Cologne Faculty of Medicine, Germany) - “Plasticity of neural circuits for oxytocin release and maternal behavior”
- Nicolas Gutierrez-Castellanos (Champalimaud Foundation, Lisbon, Portugal) - “To mate or to reject? Answers from a hypothalamic subregion involved in female sexual behavior”
- Anna Hobbiss (Champalimaud Foundation, Lisbon, Portugal) - “Actively Frozen – a novel pattern of leg muscle activity reveals flexible freezing states and anticipates movement onset in Drosophila”
Symposium 12 - 'Partners in crime: exploring neurobehavioral mechanisms at the intersection of stress and addiction' - Room Alcoutim
Chairs
- Marek Schwendt (Department of Psychology, University of Florida, Gainesville, USA)
- David Belin, Professor (Department of Psychology, University of Cambridge, England) - “On the neural basis of the exacerbation of the vulnerability to develop Alcohol Use Disorder by the acquisition of alcohol drinking as a self-medication strategy.”
- Margaret Davis (Department of Psychology, Yale University, USA) - “In vivo evidence for dysregulation of mGluR5 in PTSD as a biomarker of suicidal ideation.”
- Maria Aguilar, Professor (Department of Psychobiology, University of Valencia, Spain) - “Vulnerability vs resilience to the depression-like effects of social defeat stress predicts sensitivity to cocaine reward in mice.”
- Francesca Mottarlini (Università degli Studi di Milano, Italy) - “The Nucleus Accumbens Core as a hub of serotonin and glutamate interaction in the transition toward addiction”
12:30 - 13:30
Lunch break
"The Art of Science" - Grafitti FRM 2023
13:30 - 15:00
Symposium 13 - 'Astroglial networks in the basal ganglia: from the synapse to behavior' - Room Monchique
Chairs
- Marta Navarrete (Instituto Cajal, CSIC, Madrid, Spain)
- Ana Covelo (University of Bordeaux, France) - “Astroglial CB1: sex-specific control of plasticity and amphetamine-induced behaviour”
- Edgar Soria (Ikerbasque, Basque Foundation for Science, Spain) - “Cannabinergic control of memory: the “where” matters”
- Marta Navarrete (Instituto Cajal, CSIC, Spain) - “AstroLight Illuminates the Way: Catching and Modulating Astrocytic Ensembles for Behavioral Control in the Nucleus Accumbens”
- Daniela Sofia da Costa Abreu (Life and Health Sciences Research Institute, ICVS, University of Minho, Portugal) - "The involvement of astrocyte calcium-dependent signaling in fear memory"
Symposium 14 - 'The excitatory/inhibitory imbalance and cognitive dysfunction: a cell type-specific perspective' - Auditorium
Chairs
- Inna Gaisler-Salomon (University of Haifa, Israel)
- Luísa Lopes (Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisbon, Portugal) - "The aged glutamatergic synapse and its impact on memory"
- Wen-Jun Gao (Drexel University College of Medicine, USA) - “Pharmacogenetic activation of parvalbumin interneurons in the prefrontal cortex rescues cognitive deficits induced by adolescent MK801 administration”
- Inna Gaisler-Salomon (University of Haifa, Israel) - “Long-lasting impact of NMDA receptor blockade on cognitive and social abilities: endocannabinoid-mediated reversal and cell-type specific mechanisms”
- Jeffrey Conn (Vanderbilt University, USA) - Regulation of excitatory/inhibitory balance by metabotropic glutamate receptors: implications for treatment of cognitive disruption in schizophrenia patients.
- Sara C Calafate (VIB Center for Brain & Disease Research, Austria) - "Sleep-active hypothalamic MCH-system modulates hippocampal synaptic plasticity and is vulnerable in early Alzheimer’s Disease"
Symposium 15 - 'Environmental impact on brain health - focus on air pollution' - Room Tavira
Chairs
- Katja Kanninen (University of Eastern Finland, Joensuu, Kuopio, Finland)
- John Andersson (Dept. of Psychology, Umeå University, Sweden) - “Epidemiological studies link air pollution to brain health impairments”
- Roel Schins (Leibniz Research Institute for Environmental Medicine, Germany) - “Air pollution exposure effects on the brain in mouse models of disease”
- Remco HS Westerink (Institute for Risk Assessment Sciences, Utrecht University, Netherlands) - “Impact of traffic-derived exhaust fumes on neuronal activity in vitro”
- Liudmila Saveleva (A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Finland) - “Urban air nanoparticulate matter affects mouse astrocytes transcriptome by inducing xenobiotic and oxidative stress responses”
- Dounia Chater (Institut Mondor de Recherche Biomédicale, Université Paris-Est Créteil, France) - “In utero exposure to air pollution affect social behavior, brain transcriptome and neuroinflammation in mice”
Symposium 16 - 'Developing therapeutic interventions for rare brain diseases using cutting edge technologies - Room Alcoutim
Chairs
- Udai Pandey (University of Pittsburgh Medical Center, Pittsburgh PA, USA)
- Udai Pandey (University of Pittsburgh Medical Center, Pittsburgh, USA) - "Identifying hidden GEMs in neurological diseases"
- Maria Pennuto (University of Padova, Padova, Italy) - "Gene therapy development in preclinical models of neurodegenerative diseases"
- Pietro Chiurazzi (Università Cattolica del Sacro Cuore, Rome, Italy) - Fragile X syndrome: tackling a brain disorder without gene therapy.
- Débora Lanznaster (iBrain, Université de Tours, France) - "Phage display-derived intrabodies targeting wildtype TDP-43 present therapeutic effects in different cell models of TDP-43 proteinopathies"
15:00 - 16:00
Plenary Lecture 4 - "The neurobiology of individuality" - Auditorium
Chairs
- Sara Xapelli (Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisboa, Portugal)
- João O. Malva (Faculdade de Medicina, Universidade de Coimbra)
- Gerd Kempermann (Center for Regenerative Therapies TU Dresden, Germany)
16:00 - 16:15
ALBA-FKNE Diversity Prize Ceremony - Auditorium
Speaker(s)
- Carmen Sandi (EPFL, Switzerland)
- Andrew Lin (University of Sheffield, UK)
16:15 - 16:30
Break
16:30 - 17:30
Poster Session IV - Room Silves
European Research Council Executive Agency Workshop - Funding opportunities by the ERCRoom Tavira
European Research Council Executive Agency Workshop - Funding opportunities by the ERCRoom Tavira
Speaker(s)
- Alessandra Ferrari (Team Leader at European Research Council (ERC), Belgium)
- Elena Cattaneo (University of Milano, Italy)
17:30 - 18:30
Chairs
- Irene Tracey (University of Oxford, United Kingdom)
- Ole Kiehn (Department of Neuroscience, University of Copenhagen, Denmark and Department of Neuroscience, Karolinska Institutet, Sweden)
20:30
Gala Dinner
Friday 5 May | Salgados Palace & Congress Center
08:30 - 09:30
Plenary Lecture 5 - "Regulation of glia homeostasis by RhoGTPase signalling" - Auditorium
Chairs
- Tiago F. Outeiro (University Medical Center Goettingen, Goettingen, Germany)
- Inês Araújo (University of Algarve, Portugal)
- João Relvas (i3S -Institute for Research & Innovation in Health, Porto, Portugal)
09:30 - 11:00
Symposium 17 - 'Invasive and noninvasive brain stimulation therapies in Neuropsychiatric disorders - Room Monchique
Chairs
- Marcelo D. Mendonça (Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisbon, Portugal)
- Jonathan Schor (University of California, USA) - “Circuit Dissection of Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) with Optical Recordings“
- Susanne Knorr (Department of Neurology, University Hospital of Würzburg, Germany) - “DBS effects on behavioral and multiscale neurobiological levels in rodent models of movement disorders”
- Albino Oliveira-Maia (Champalimaud Foundation, Lisbon, Portugal) - “Brain connectivity informs the treatment of neuropsychiatric disorders”
- Miguel Aroso (Instituto de Engenharia Biomédica, University of Porto, Portugal) - “Bringing astrocytes into the spotlight of electrical brain stimulation therapy”
Symposium 18 - 'Molecular and cellular mechanisms of memory persistence - Auditorium
Chairs
- Ana M.M. Oliveira (Institute of Neurobiology, IZN Heidelberg, Heidelberg University, Germany)
- Ana M.M. Oliveira, (Central Institute of Mental Health, Heidelberg University, Germany) - “DNA methylation regulates memory duration and engram stability”
- Michel van den Oever (Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Netherlands) - “Experience-dependent progressive neuroadaptations in cortical engram cells that support memory persistence”
- Ron Refaeli (Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Israel) - “Engram Stability and Maturation During Systems Consolidation Underlies Remote Memory, and Is Affected by Astrocytes”
- Kubra Gulmez Karaca (Donders Institute, Netherlands) - “Norepinephrine effects on memory engram specificity over time”
Symposium 19 -'Advances in Polyglutamine diseases research' - Room Tavira
Chairs
- Carlos A. Matos (Algarve Biomedical Center Research Institute, University of Algarve, Portugal)
- David Brito (Algarve Biomedical Center Research Institute, University of Algarve, Portugal)
- Lynn Raymond (Centre for Huntington Disease, The University of British Columbia, Canada) - "Targeting mechanisms of synaptic and circuit changes in early Huntington’s disease"
- Hilmar Bading (University of Heidelberg, Germany) - "NMDAR/TRPM4 interface inhibitors: new pharmacological principle for treatment of Huntington’s Disease"
- José Laffita-Mesa (Karolinska Institute, Sweden) - "From founder effects to a comprehensive understanding of the physiological and pathological functions of ATXN2"
- Catarina Miranda (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal) - "Induction of mutant atxin-3 uptake, and late autophagy and mitophagy improvements may contribute to reduction of mutant ataxin-3 levels in Spinocerebellar Ataxia Type-3 models."
FENS CHET Symposium - A world full of opportunities: What career paths for neuroscientists? - Room Alcoutim
Chairs
- Dirk Schubert (Member of the FENS Committee on Higher Education and Training (CHET), RadboudUMC Nijmegen, Netherlands)
- Dr. Britt Mossink (Janssen Pharmaceutical Companies of Johnson & Johnson, The Netherlands)
- Dr. Clara Garcia Gorro (AbbVie, England)
- Eidan Tzdaka (Drowzee, Oslo, Norway)
- Dr. Alessandra Ferrari (Team Leader at European Research Council (ERC), Belgium)
11:00 - 11:15
Break
11:15 - 12:45
Symposium 20 -'RNA-binding prteins and stress granules in brain plasticity and pathology' - Room Monchique
Chairs
- Ioannis Sotiropoulos (Institute of Biosciences and Applications, NCSR Demokritos, Athens, Greece)
- Susanne Wegmann (Deutsches Zentrum f. Neurodegenerative Erkrankungen, Germany) - “Condensed phase interactions of the microtubule associated protein Tau”
- Joana Silva (Life and Health Sciences Research Institute (ICVS), University of Minho, Portugal) - "Chronic stress signaling and Stress granules as key players in Alzheimer’s disease brain pathology"
- Adriana Marcelo (Algarve Biomedical Center Research Institute, University of Algarve, Portugal) - "Unraveling the role of RBPs in Machado-Joseph disease: from pathogenesis to therapeutic targets"
- Georgia Papadimitriou (Institute of Biosciences and Applications, Greece) - "Dissecting the interplay of Tau & RNA granules in stressed brain"
Symposium 21 - 'From transplantation to reprogramming: avenues to brain repair' - Auditorium
Chairs
- Sofia Grade (Institute of Molecular Biotechnology (IMBA), Austria)
- Daniel Tornero (Department of Biomedical Sciences. Faculty of Medicine, University of Barcelona, Spain)
- Benedikt Berninger (King’s College London, England) - "Engineering new interneurons for the postnatal cerebral cortex."
- Daniel Tornero (Institute of Neuroscience, University of Barcelona, Spain) - "Bi-directional reconstruction of stroke-damaged brain circuitry using Human Neural Stem Cells"
- Sofia Grade (Institute of Molecular Biotechnology Vienna, Austria) - "Understanding synaptic integration of transplanted neurons into damaged circuits."
- Daniel del Toro (Institute of Neurosciences, University of Barcelona, Spain) - "Increased neurogenesis and behavior performance by in vivo reprogramming"
- Eilis Dowd (University of Galway, Ireland) - "Human induced pluripotent stem cell-derived repair of the Parkinsonian rat brain is enhanced by delivery of cells in a neurotrophin-enriched hydrogel"
Symposium 22 - 'New insights into the modulation of reward and aversion encoding in the brainstem' - Room Tavira
Chairs
- Bárbara Coimbra (Life and Health Sciences Research Institute (ICVS), University of Minho, Portugal)
- Bárbara Coimbra (Life and Health Sciences Research Institute (ICVS), University of Minho, Portugal) - "Laterodorsal tegmentum-Nucleus accumbens projections underlie cocaine- induced preference"
- Jacques Barik (Institut de Pharmacologie Moléculaire & Cellulaire, CNRS, Université Côte, France) - “Nicotine biaises motivational valence by altering brainstem cholinergic signals”
- Juan Mena-Segovia (Center for Molecular and Behavioral Neuroscience, Rutgers University, USA) - "Midbrain cholinergic modulation of thalamic circuits."
- Nicole Ortiz (Sorbonne Université, France) - "Identifying the neural correlates of an aversive response in the Habenulo-Interpeduncular pathway of the zebrafish larvae"
- Sian Nina Duss (Neuroscience Center Zurich, University of Zurich, Switzerland) - "Brainstem noradrenaline dynamics during an approach-avoidance task"
ALBA Network workshop - ALBA Mentoring Circles: discussions on diversity and inclusion in neuroscience - Room Albufeira
Chairs
- Carmen Sandi (EPFL, Switzerland)
- Emma Yhnell (Cardiff University, UK)
- Andrew Lin (University of Sheffield, UK)
- Caroline Menard (CERVO Brain Research Center, Canada)
- Catarina Miranda (Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Portugal)
- Maria Inês Barros (Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Portugal)
- Marlene Santos (Polytechnic Institute of Porto, Portugal)
- Sara Xapelli (Instituto de Medicina Molecular iMM, Faculdade de Medicina, Universidade de Lisboa, Portugal)
- Stamatina Tzanoulinou (University of Lausanne, Switzerland)
12:45 - 13:45
Lunch break
13:45 - 16:30
Extended Symposia I - Neuronal mechanisms of social behavior - Auditorium
Part I - Neural circuit mechanisms of social behavior
Chairs
- Jan Rodriguez Parkitna (Maj Institute of Pharmacology Polish Academy of Sciences, Krakow, Poland)
- Ewelina Knapska (Nencki Institute of Experimental Biology Polish Academy of Sciences, Poland) - "Social learning about rewards"
- Tobias Kalenscher (Institute of Experimental Psychology, Heinrich-Heine-University, Germany) - "Behavioral and brain mechanisms of social learning"
- Hanna Hörnberg (Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Germany) - "Molecular mechanisms of social behaviors"
- Clara Howcroft Ferreira (Champalimaud Foundation, Lisbon, Portugal) - "Social modulation of defensive responses to a threat"
Part II - Neuronal mechanisms of social beahvior
Chairs
- Constanze Lenschow, Otto-von- Guericke (University Magdeburg, Institute of Biology, Magdeburg, Germany)
- Sanja Bauer-Mikulovic (Leibniz Institute for Neurobiology, Germany) - "Behavioral variables and neural circuits underlying helping behavior in mice."
- Yoh Isogai (Sainsbury Wellcome Centre, England) - "Molecular and neural detection of pheromones"
- Felix Leroy (Instituto de Neurociencias en Alicante, Spain) - "Neuronal circuits regulating social preferences"
- Ana Rita Mendes (Champalimaud Foundation, Lisbon, Portugal) - "Spinal control of copulatory behavior and sexual excitation"
Extended Symposia II - Myelin plasticity and regenerative approaches - Room Tavira
Part I - Myelin regenerative approaches to prevent axonal loss
Chairs
- Alerie Guzmán de la Fuente (Institute for Health and Biomedical Sciences of Alicante, Spain)
- Jose A. Gomez-Sanchez (Instituto de Investigación Sanitaria y Biomédica de Alicante and Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Alicante, Spain)
- Björn Neumann (Altos Labs, England) - “Lessons from the ageing and functional rejuvenation of Oligodendrocyte Progenitor Cells”
- Ashwin Woodhoo (CIMUS – Universidad de Santiago de Compostela, Spain) - “The post-translational modification Neddylation is a multifaceted regulator of Schwann cell myelination and nerve repair”
- Alerie Guzman de la Fuente (Institute for Health and Biomedical Sciences of Alicante, Spain) - “T cell and Oligodendrocyte progenitor cell crosstalk in remyelination”
- Tejaswini Kakunuri (Institute for Advanced Biosciences, University Grenoble Alpes, France) - "Inhibition of Chondroitin Sulfate Proteoglycans to Promote Regeneration in the CNS in Multiple Sclerosis"
Part II - Myelin structural plasticity in neuronal circuit repair: from molecular to functional aspect
Chairs
- Juliana M Rosa (National Hospital of Paraplegics, Toledo, Spain)
- Enrica Boda (University of Turin, Italy) - "Molecular and functional heterogeneity in dorsal and ventral oligodendrocyte progenitor cells of the mouse forebrain in response to DNA damage"
- Fernando de Castro (Cajal Institute, Madrid, Spain) - "Genetic approaches to study the roles of anosmin-1 and Shh in oligodendrogliogenesis, myelination and remyelination."
- Juliana M Rosa (National Hospital of Paraplegics, Toledo, Spain) - "Adaptive myelin plasticity and glial-glial crosstalk as regulators of neuronal excitability following sensory deprivation."
- Taekyun SHIN Jeju (National University, Republic of Korea) - “Single-cell deep phenotyping of cellular functionalities”
Special symposium – Neuroscience communication: what, how and why? (Organised by the FENS Communication Committee) - Room Alcoutim
Chairs
- Rui Rodrigues (INSERM, Neurocentre Magendie, Bordeaux, France)
- Elodie Chabrol (Freelance Consultant/Science Communicator) - "Practical tips for effective and successful science communication"
- Carlos Catalão Alves (NOVA University Lisbon, Portugal) - "Understand your audience: communication strategies for neuroscientists"
- Emma Yhnell (Cardiff University, England) - “But why? The importance of communicating neuroscience"
- Pedro Russo (Leiden University, Netherlands) - "The academic context for science communication: theory & practice"
Chairs
- Flavio Donato, FENS-Kavli Network of Excellence (FKNE)
- Flavio Donato (Biozentrum, University of Basel, Switzerland) - “Multiple memory traces in the hippocampal engram”.
- Andrew Lin (University of Sheffield, England) - “Sparse coding for odour-specific memories through homeostatic plasticity”.
- Maximilian Jösch (Institute of Science and Technology (IST), Austria) - “Gap-junctions arbitrate binocular course control in flies”.
- Julie Duqué (Université catholique Louvain, Belgium) - “Transcranial magnetic stimulation investigation of actionpreparation in humans”
- Martin Dresler (Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Netherlands) - “Why we sleep”.
- Simona Lodato (Department of Biomedical Sciences, Humanitas University; Humanitas Clinical and Research Center, Italy) - “Decoding the molecular underpinning of spontaneous activity in the developingcerebral cortex”
16:30 - 17:30
Plenary Lecture 6 - "Transforming brain cholesterol into a therapy for neurodegenerative diseases: the case of Huntington's Disease" - Auditorium
Chairs
- Ana Cristina Rego (Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Portugal)
- Alberto Pascual (Instituto de Biomedicina de Sevilla (IBiS), Spain)
- Elena Cattaneo (University of Milano, Italy)
17:30 - 17:45
Closing Session
Chairs
- Clévio Nóbrega, FRM 2023 Chair
- Ana Cristina Rego, SPN President
- New Elected SPN President
SATELLITE EVENTS:
Monday 1 May | University of Algarve
09:00 - 19:00
ENCODS 2023
Tuesday 2 May | Albufeira Municipal Auditorium
13:30 - 20:00
VII Symposium of the The Portuguese Glial Network
Tuesday 5-8 May | Salgados Palace & Congress Center
17:00 - 20:00
5 May - RobustCircuit Workshop - “Web technologies for Cognitive Science”
09:30-19:30
6 May - RobustCircuit Workshop - “Web technologies for Cognitive Science”
10:00-22:30
7 May - RobustCircuit Workshop - “Web technologies for Cognitive Science”
09:00-11:00
8 May - RobustCircuit Workshop - “Web technologies for Cognitive Science”
* The presented programme is not definitive and may eventually be changed or updated.
